human HAL shRNA silencing AAV

Name
AAV-h-HAL-shRNA

Cat No
shAAV-210769

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human HAL.

shAAV-210769

AAV-h-HAL-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HAL (histidine ammonia-lyase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HIS; HSTD

Description (Vector)

Histidine ammonia-lyase is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. Histidine ammonia-lyase defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluids. Several transcript variants encoding different isoforms have been found for this gene.

Gene ID

3034

Gene Name (Vector)

histidine ammonia-lyase

Gene Symbol

HAL

HGNC ID

HGNC:4806

ORF Size (aa)

1974

ORF Size (bp)

1974 bp

RefSeq ID

NM_002108

RefSeq Synonyms

NM_002108, NM_001258334, NM_001258333, BC096099, BC096098, BC096097,

Species

human

UniGene ID

Hs.190783

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.