human H2AFB1 shRNA silencing AAV

Name
AAV-h-H2AFB1-shRNA

Cat No
shAAV-210729

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human H2AFB1.

shAAV-210729

AAV-h-H2AFB1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human H2AFB1 (H2A histone family member B1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

H2A.Bbd

Description (Vector)

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. This gene is part of a region that is repeated three times on chromosome X, once in intron 22 of the F8 gene and twice closer to the Xq telomere. This record represents the most centromeric copy which is in intron 22 of the F8 gene.

Gene ID

474382

Gene Name (Vector)

H2A histone family member B1

Gene Symbol

H2AFB1

HGNC ID

HGNC:22516

ORF Size (aa)

348

RefSeq ID

NM_001017990

RefSeq Synonyms

NM_001017990, BC128034,

Species

human

UniGene ID

Hs.592246

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.