human H1FOO shRNA silencing AAV

Name
AAV-h-H1FOO-shRNA

Cat No
shAAV-210726

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human H1FOO.

shAAV-210726

AAV-h-H1FOO-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human H1FOO (H1 histone family member O, oocyte specific). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

H1.8; H1oo; osH1

Description (Vector)

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The protein encoded is a member of the histone H1 family. This gene contains introns, unlike most histone genes. The protein encoded is a member of the histone H1 family. The related mouse gene is expressed only in oocytes.

Gene ID

132243

Gene Name (Vector)

H1 histone family member O, oocyte specific

Gene Symbol

H1FOO

HGNC ID

HGNC:18463

ORF Size (aa)

624

RefSeq ID

NM_153833

RefSeq Synonyms

NM_153833, NM_001308262, BC047943,

Species

human

UniGene ID

Hs.97358

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.