human GYPC shRNA silencing AAV

Name
AAV-h-GYPC-shRNA

Cat No
shAAV-210708

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human GYPC.

shAAV-210708

AAV-h-GYPC-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GYPC (glycophorin C (Gerbich blood group)). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CD236; CD236R; GE; GPC; GPD; GYPD; PAS-2; PAS-2'

Description (Vector)

Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants.

Gene ID

2995

Gene Name (Vector)

glycophorin C (Gerbich blood group)

Gene Symbol

GYPC

HGNC ID

HGNC:4704

ORF Size (aa)

387

RefSeq ID

NM_002101

RefSeq Synonyms

NM_016815, NM_002101, NM_001256584, BC106051, BC104247, BC104246,

Species

human

UniGene ID

Hs.59138

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.