human GRK5 shRNA silencing AAV

Name 
AAV-h-GRK5-shRNA
Cat No 
shAAV-210539
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human GRK5.

shAAV-210539
AAV-h-GRK5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GRK5 (G protein-coupled receptor kinase 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GPRK5
Description (Vector)
GRK5 encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs).
Gene ID
2869
Gene Name (Vector)
G protein-coupled receptor kinase 5
Gene Symbol
GRK5
HGNC ID
HGNC:4544
ORF Size (aa)
1773
ORF Size (bp)
1773 bp
RefSeq ID
NM_005308
RefSeq Synonyms
NM_005308, BC064506,
Species
human
UniGene ID
Hs.524625

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.