human GRIA3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human GRIA3.
shAAV-210507
AAV-h-GRIA3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human GRIA3 (glutamate ionotropic receptor AMPA type subunit 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GluA3; GLUR-C; GLUR-K3; GLUR3; GLURC; MRX94
Description (Vector)
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.
Gene ID
2892
Gene Name (Vector)
glutamate ionotropic receptor AMPA type subunit 3
Gene Symbol
GRIA3
HGNC ID
HGNC:4573
ORF Size (aa)
2475
ORF Size (bp)
2475 bp
RefSeq ID
NM_000828
RefSeq Synonyms
NM_007325, NM_001256743, NM_000828, BC117464,
Species
human
UniGene ID
Hs.377070
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.