human GORAB shRNA silencing AAV

Name 
AAV-h-GORAB-shRNA
Cat No 
shAAV-210177
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human GORAB.

shAAV-210177
AAV-h-GORAB-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GORAB (golgin, RAB6 interacting). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GO; hNTKL-BP1; N-terminal kinase-like-binding protein 1; NTKL-binding protein 1; NTKLBP1; NTKL-BP1; RAB6-interacting golgin; SCY1-like 1-binding protein 1; SCYL1-binding protein 1; SCYL1BP1; SCYL1-BP1
Description (eCommerce)
GORAB is a member of the golgin family, a group of coiled-coil proteins localized to the Golgi. GORAB may function in the secretory pathway. GORAB localizes to the cytoplasm and was identified by interactions with the N-terminal kinase-like protein. It may function in mitosis [taken from NCBI Entrez Gene (Gene ID: 92344)].
Description (Vector)
GORAB encodes a member of the golgin family, a group of coiled-coil proteins localized to the Golgi. The encoded protein may function in the secretory pathway. The encoded protein, which also localizes to the cytoplasm, was identified by interactions with the N-terminal kinase-like protein, and thus it may function in mitosis. Mutations in this gene have been associated with geroderma osteodysplastica. Alternatively spliced transcript variants have been described.
Gene ID
92344
Gene Name (eCommerce)
golgin, RAB6 interacting
Gene Name (Vector)
golgin, RAB6 interacting
Gene Symbol
GORAB
HGNC ID
HGNC:25676
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
741
ORF Size (bp)
741 bp
Protein Name (eCommerce)
RAB6-interacting golgin
RefSeq ID
NM_152281
RefSeq Synonyms
NM_152281, NM_001320252, NM_001146039, BC064945, BC047476,
Research Areas
Golgi Apparatus
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
GORAB is a member of the golgin family, a group of coiled-coil proteins localized to the Golgi. GORAB may function in the secretory pathway. GORAB localizes to the cytoplasm and was identified by interactions with the N-terminal kinase-like protein. It may function in mitosis [taken from NCBI Entrez Gene (Gene ID: 92344)].
UniGene ID
Hs.183702
UniProt ID (eCommerce)
Q5T7V8

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.