human GNL1 shRNA silencing AAV

Name
AAV-h-GNL1-shRNA

Cat No
shAAV-210123

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human GNL1.

shAAV-210123

AAV-h-GNL1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GNL1 (G protein nucleolar 1 (putative)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

90

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

GTP-binding protein HSR1; guanine nucleotide-binding protein-like 1; HSR1; HSR1 GTP-binding protein

Description (eCommerce)

GNL1 (guanine nucleotide-binding protein-like 1) is a GTP-binding protein. Its gene has been found to map to the human major histocompatibility complex class I region indicating that it may have a role in the signal transduction of T-cell mediated immunity.

Description (Vector)

The GNL1 gene, identified in the human major histocompatibility complex class I region, shows a high degree of similarity with its mouse counterpart. The GNL1 gene is located less than 2 kb centromeric to HLA-E, in the same transcriptional orientation. GNL1 is telomeric to HLA-B and HLA-C.

Gene ID

2794

Gene Name (eCommerce)

G protein nucleolar 1 (putative)

Gene Name (Vector)

G protein nucleolar 1 (putative)

Gene Symbol

GNL1

HGNC ID

HGNC:4413

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1824

ORF Size (bp)

1824 bp

Protein Name (eCommerce)

Guanine nucleotide-binding protein-like 1

RefSeq ID

NM_005275

RefSeq Synonyms

NM_005275, BC018366, BC013959,

Research Areas

DNA Damage/Repair,Immunology,Signal Transduction

Research Areas (Faceted)

cell_biology,genetics,immunology,signal_transduction,transcription_translation

Species

human

Target Sentence

GNL1 (guanine nucleotide-binding protein-like 1) is a GTP-binding protein. Its gene has been found to map to the human major histocompatibility complex class I region indicating that it may have a role in the signal transduction of T-cell mediated immunity.

UniGene ID

Hs.83147

UniProt ID (eCommerce)

P36915

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.