human GJB3 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-209925
Availability:
4-5 weeks
Name:
AAV-h-GJB3-shRNA
This is an AAV expressing shRNA for silencing of Human GJB3.
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Product Info
- Knockdown
- >70% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- GJB3
- Gene Name
- gap junction protein beta 3
- Gene ID
- 2707
- Gene Synonyms
- CX31; DFNA2; DFNA2B; EKV
- ORF Size
- 813 bp
- RefSeq#
- NM_024009
- Gene Description
- GJB3 is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene can cause non-syndromic deafness or erythrokeratodermia variabilis, a skin disorder. Alternative splicing results in multiple transcript variants encoding the same protein.
- UniGene ID
- Hs.522561
- HGNC ID
- HGNC:4285
Related Products
Product | Cat No. |
---|---|
AAV-h-GJB3 | AAV-209925 |
AAV-m-GJB3 | AAV-260137 |
Ad-h-GJB3 | ADV-209925 |
Ad-m-GJB3 | ADV-260137 |
AAV-m-GJB3-shRNA | shAAV-260137 |
Ad-h-GJB3-shRNA | shADV-209925 |
Ad-m-GJB3-shRNA | shADV-260137 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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