human GJA4 shRNA silencing AAV

Name
AAV-h-GJA4-shRNA

Cat No
shAAV-209915

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human GJA4.

shAAV-209915

AAV-h-GJA4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GJA4 (gap junction protein alpha 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CX37

Description (Vector)

GJA4 encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction.

Gene ID

2701

Gene Name (Vector)

gap junction protein alpha 4

Gene Symbol

GJA4

HGNC ID

HGNC:4278

ORF Size (aa)

1002

ORF Size (bp)

1002 bp

RefSeq ID

NM_002060

RefSeq Synonyms

NM_002060, BC072389, BC027889,

Species

human

UniGene ID

Hs.296310

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.