human GIMAP1 shRNA silencing AAV

Name
AAV-h-GIMAP1-shRNA

Cat No
shAAV-209877

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human GIMAP1.

shAAV-209877

AAV-h-GIMAP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GIMAP1 (GTPase, IMAP family member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HIMAP1; IAN2; IMAP1; IMAP38

Description (Vector)

GIMAP1 encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. GIMAP1 is thought to be involved in the differentiation of T helper (Th) cells of the Th1 lineage, and the related mouse gene has been shown to be critical for the development of mature B and T lymphocytes. Read-through transcription exists between this gene and the downstream GIMAP5 (GTPase, IMAP family member 5) gene.

Gene ID

170575

Gene Name (Vector)

GTPase, IMAP family member 1

Gene Symbol

GIMAP1

HGNC ID

HGNC:23237

ORF Size (aa)

921

ORF Size (bp)

921 bp

RefSeq ID

NM_130759

RefSeq Synonyms

NM_130759, BC040736,

Species

human

UniGene ID

Hs.647087

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.