human GHRH shRNA silencing AAV

Cat. No: shAAV-209865

Availability: 6-8 weeks

Name: AAV-h-GHRH-shRNA

This is an AAV expressing shRNA for silencing of Human GHRH.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: GHRH
Gene Name: growth hormone releasing hormone
Gene ID: 2691
Gene Synonyms: GHRF; GRF; INN
ORF Size: 324 bp
RefSeq#: NM_021081
Gene Description: GHRH belongs to the glucagon family and is a preproprotein that is produced in the hypothalamus. The preproprotein is cleaved to form a 44 aa factor, also called somatocrinin, that acts to stimulate growth hormone release from the pituitary. Variant receptors for somatocrinin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism.
UniGene ID: Hs.37023
HGNC ID: HGNC:4265