human GEMIN8 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human GEMIN8.
shAAV-209810
AAV-h-GEMIN8-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human GEMIN8 (gem nuclear organelle associated protein 8). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
FAM51A1
Description (Vector)
GEMIN8 is part of the SMN complex, which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre-mRNA splicing in the nucleus. The encoded protein binds to both SMN1 and the GEMIN6/GEMIN7 heterodimer, mediating their interaction. This protein is found in nuclear Gemini of Cajal bodies (gems) and in the cytoplasm. Three transcript variants encoding the same protein have been found for this gene.
Gene ID
54960
Gene Name (Vector)
gem nuclear organelle associated protein 8
Gene Symbol
GEMIN8
HGNC ID
HGNC:26044
ORF Size (aa)
729
ORF Size (bp)
729 bp
RefSeq ID
NM_017856
RefSeq Synonyms
NM_017856, NM_001042480, NM_001042479, BC020785, BC014324, BC003607,
Species
human
UniGene ID
Hs.592237
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.