human GEFT shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ARHGEF25.
shAAV-209803
AAV-h-GEFT-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ARHGEF25 (Rho guanine nucleotide exchange factor 25). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GEFT; p63RhoGEF
Description (Vector)
Rho GTPases alternate between an inactive GDP-bound state and an active GTP-bound state, and GEFs facilitate GDP/GTP exchange. This gene encodes a guanine nucleotide exchange factor (GEF) which interacts with Rho GTPases involved in contraction of vascular smooth muscles, regulation of responses to angiotensin II and lens cell differentiation. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
115557
Gene Name (Vector)
Rho guanine nucleotide exchange factor 25
Gene Symbol
ARHGEF25
HGNC ID
HGNC:30275
ORF Size (aa)
1425
ORF Size (bp)
1425 bp
RefSeq ID
NM_001111270
RefSeq Synonyms
NM_182947, NM_001111270, BC047559, BC012860,
Species
human
UniGene ID
Hs.61581
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.