human GC shRNA silencing AAV

Name
AAV-h-GC-shRNA

Cat No
shAAV-209727

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human GC.

shAAV-209727

AAV-h-GC-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GC (GC, vitamin D binding protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

DBP; DBP/GC; Gc-MAF; GcMAF; GRD3; HEL-S-51; VDBG; VDBP

Description (Vector)

GC belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene ID

2638

Gene Name (Vector)

GC, vitamin D binding protein

Gene Symbol

HGNC ID

HGNC:4187

ORF Size (aa)

1425

ORF Size (bp)

1425 bp

RefSeq ID

NM_000583

RefSeq Synonyms

NM_001204307, NM_001204306, NM_000583, BC057228,

Species

human

UniGene ID

Hs.418497

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.