human GBL shRNA silencing AAV

Name 
AAV-h-GBL-shRNA
Cat No 
shAAV-209711
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MLST8.

shAAV-209711
AAV-h-GBL-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MLST8 (MTOR associated protein, LST8 homolog). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
64
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
G protein beta subunit-like; gable; GbetaL; GBL; LST8; mammalian lethal with SEC13 protein 8; mLST8; POP3; protein GbetaL; target of rapamycin complex subunit LST8; TORC subunit LST8; WAT1
Description (eCommerce)
GbetaL (G-protein beta-subunit-like) is a member of the WD-repeat family of proteins that share a highly conserved tryptophan-aspartate repeating motif that mediates the assembly of multiprotein factors.
Gene ID
64223
Gene Name (eCommerce)
MTOR associated protein, LST8 homolog
Gene Name (Vector)
MTOR associated protein, LST8 homolog
Gene Symbol
MLST8
HGNC ID
HGNC:24825
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
981
ORF Size (bp)
981 bp
Protein Name (eCommerce)
Target of rapamycin complex subunit LST8
RefSeq ID
NM_022372
RefSeq Synonyms
NM_022372, NM_001199175, NM_001199174, NM_001199173, BC088354, BC052292, BC020499, BC017119, BC001313,
Research Areas
Autophagy,B-cell Receptor Signaling,Cancer,Cytoskeleton,EGFR Signaling,EGFR Signaling in Cancer,Fc Receptor Signaling,FGF Signaling,HGF Signaling,IFN Signaling,IGF-1 Signaling,Immunology,Innate Immunity,Insulin Signaling,LKB1 Signaling,mTOR Signaling,Neurobiology,NGF Signaling,PDGF Signaling,PI3K/Akt Signaling,PI3K-AKT Signaling in Cancer,SCF-KIT Signaling,Signal Transduction,Toll-like Receptor Signaling
Research Areas (Faceted)
cancer,cell_biology,immunology,neurobiology,signal_transduction,stem_cell_biology
Species
human
Target Sentence
GbetaL (G-protein beta-subunit-like) is a member of the WD-repeat family of proteins that share a highly conserved tryptophan-aspartate repeating motif that mediates the assembly of multiprotein factors.
UniGene ID
Hs.29203
UniProt ID (eCommerce)
Q9BVC4

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.