human G6PC2 shRNA silencing AAV

Name
AAV-h-G6PC2-shRNA

Cat No
shAAV-209480

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human G6PC2.

shAAV-209480

AAV-h-G6PC2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human G6PC2 (glucose-6-phosphatase catalytic subunit 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

IGRP

Description (Vector)

G6PC2 encodes an enzyme belonging to the glucose-6-phosphatase catalytic subunit family. These enzymes are part of a multicomponent integral membrane system that catalyzes the hydrolysis of glucose-6-phosphate, the terminal step in gluconeogenic and glycogenolytic pathways, allowing the release of glucose into the bloodstream. The family member encoded by this gene is found in pancreatic islets and does not exhibit phosphohydrolase activity, but it is a major target of cell-mediated autoimmunity in diabetes. Several alternatively spliced transcript variants of this gene have been described, but their biological validity has not been determined.

Gene ID

57818

Gene Name (Vector)

glucose-6-phosphatase catalytic subunit 2

Gene Symbol

G6PC2

HGNC ID

HGNC:28906

ORF Size (aa)

1068

ORF Size (bp)

1068 bp

RefSeq ID

NM_021176

RefSeq Synonyms

NM_021176, NM_001081686, BC113376, BC104778,

Species

human

UniGene ID

Hs.283963

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.