human FTO shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human FTO.
shAAV-209388
AAV-h-FTO-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human FTO (FTO, alpha-ketoglutarate dependent dioxygenase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ALKBH9; BMIQ14; GDFD
Description (Vector)
FTO is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.
Gene ID
79068
Gene Name (Vector)
FTO, alpha-ketoglutarate dependent dioxygenase
Gene Symbol
FTO
HGNC ID
HGNC:24678
ORF Size (aa)
1518
ORF Size (bp)
1518 bp
RefSeq ID
NM_001080432
RefSeq Synonyms
NM_001080432, BC153032, BC148442,
Species
human
UniGene ID
Hs.528833
Recently Viewed Products
Ad-CMV-iCre
Cat No: 1045
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
Ad-CMV-Rb
Cat No: 1043
Ad-CMV-p27
Cat No: 1042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.