human FNTB shRNA silencing AAV

Name 
AAV-h-FNTB-shRNA
Cat No 
shAAV-209213
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human FNTB.

shAAV-209213
AAV-h-FNTB-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FNTB (farnesyltransferase, CAAX box, beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CAAX farnesyltransferase subunit beta; epididymis secretory sperm binding protein; FPTB; FTase-beta; protein farnesyltransferase subunit beta; ras proteins prenyltransferase subunit beta
Description (eCommerce)
Protein farnesyltransferase subunit beta (FNTB) is an essential subunit of the farnesyltransferase complex. FNTB catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P49356].
Gene ID
2342
Gene Name (eCommerce)
farnesyltransferase, CAAX box, beta
Gene Name (Vector)
farnesyltransferase, CAAX box, beta
Gene Symbol
FNTB
HGNC ID
HGNC:3785
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1314
ORF Size (bp)
1314 bp
Protein Name (eCommerce)
Protein farnesyltransferase subunit beta
RefSeq ID
NM_002028
RefSeq Synonyms
NM_002028, BC020232,
Research Areas
Cell Cycle,Neurobiology,Signal Transduction
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,neurobiology,signal_transduction
Species
human
Target Sentence
Protein farnesyltransferase subunit beta (FNTB) is an essential subunit of the farnesyltransferase complex. FNTB catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P49356].
UniGene ID
Hs.632345
UniProt ID (eCommerce)
P49356

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.