human FLVCR2 shRNA silencing AAV

Name
AAV-h-FLVCR2-shRNA

Cat No
shAAV-209170

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human FLVCR2.

shAAV-209170

AAV-h-FLVCR2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FLVCR2 (feline leukemia virus subgroup C cellular receptor family member 2). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

C14orf58; CCT; EPV; FLVCRL14q; MFSD7C; PVHH

Description (Vector)

FLVCR2 encodes a member of the major facilitator superfamily. The encoded transmembrane protein is a calcium transporter. Unlike the related protein feline leukemia virus subgroup C receptor 1, the protein encoded by this locus does not bind to feline leukemia virus subgroup C envelope protein. The encoded protein may play a role in development of brain vascular endothelial cells, as mutations at this locus have been associated with proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome. Alternatively spliced transcript variants have been described.

Gene ID

55640

Gene Name (Vector)

feline leukemia virus subgroup C cellular receptor family member 2

Gene Symbol

FLVCR2

HGNC ID

HGNC:20105

ORF Size (aa)

1581

ORF Size (bp)

1581 bp

RefSeq ID

NM_017791

RefSeq Synonyms

NM_017791, NM_001195283, BC019087,

Species

human

UniGene ID

Hs.615289

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.