human FLOT1 shRNA silencing AAV

Name
AAV-h-FLOT1-shRNA

Cat No
shAAV-209156

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human FLOT1.

shAAV-209156

AAV-h-FLOT1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FLOT1 (flotillin 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

flotillin-1; integral membrane component of caveolae

Description (eCommerce)

Flotillin-1 may act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ O75955].

Description (Vector)

Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. FLOT1 encodes a caveolae-associated, integral membrane protein. The function of flotillin 1 has not been determined.

Gene ID

10211

Gene Name (eCommerce)

flotillin 1

Gene Name (Vector)

flotillin 1

Gene Symbol

FLOT1

HGNC ID

HGNC:3757

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1284

ORF Size (bp)

1284 bp

Protein Name (eCommerce)

Flotillin-1

RefSeq ID

NM_005803

RefSeq Synonyms

NM_005803, NM_001318875, BC001146,

Research Areas

Axonogenesis,EGFR Signaling,Insulin Signaling,Neurobiology,Rho Signaling,Signal Transduction

Research Areas (Faceted)

developmental_biology,neurobiology,signal_transduction

Species

human

Target Sentence

UniGene ID

Hs.179986

UniProt ID (eCommerce)

O75955

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.