human FES shRNA silencing AAV

Name 
AAV-h-FES-shRNA
Cat No 
shAAV-208913
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human FES.

shAAV-208913
AAV-h-FES-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FES (FES proto-oncogene, tyrosine kinase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
FPS
Description (Vector)
FES encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.
Gene ID
2242
Gene Name (Vector)
FES proto-oncogene, tyrosine kinase
Gene Symbol
FES
HGNC ID
HGNC:3657
ORF Size (aa)
2469
ORF Size (bp)
2469 bp
RefSeq ID
NM_002005
RefSeq Synonyms
NM_002005, NM_001143785, NM_001143784, NM_001143783, BC035357,
Species
human
UniGene ID
Hs.7636

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.