human FCRLA shRNA silencing AAV

Name
AAV-h-FCRLA-shRNA

Cat No
shAAV-208884

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human FCRLA.

shAAV-208884

AAV-h-FCRLA-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FCRLA (Fc receptor like A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

FCRL; FCRL1; FCRLb; FCRLc1; FCRLc2; FCRLd; FCRLe; FCRLM1; FCRLX; FCRX; FREB

Description (Vector)

FCRLA encodes a protein similar to receptors for the Fc fragment of gamma immunoglobulin (IgG). These receptors, referred to as FCGRs, mediate the destruction of IgG-coated antigens and of cells induced by antibodies. This encoded protein is selectively expressed in B cells, and may be involved in their development. This protein may also be involved in the development of lymphomas. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

Gene ID

84824

Gene Name (Vector)

Fc receptor like A

Gene Symbol

FCRLA

HGNC ID

HGNC:18504

ORF Size (aa)

1131

ORF Size (bp)

1131 bp

RefSeq ID

NM_032738

RefSeq Synonyms

NM_032738, NM_001184873, NM_001184872, NM_001184871, NM_001184870, NM_001184867, NM_001184866, BC006521,

Species

human

UniGene ID

Hs.266331

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.