human FABP3 shRNA silencing AAV

Name 
AAV-h-FABP3-shRNA
Cat No 
shAAV-208250
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human FABP3.

shAAV-208250
AAV-h-FABP3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FABP3 (fatty acid binding protein 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
epididymis secretory sperm binding protein;FABP11;fatty acid binding protein 11;fatty acid binding protein 3, muscle and heart;Fatty acid-binding protein 3;fatty acid-binding protein, heart;heart-type fatty acid-binding protein;H-FABP;mammary-derived growth inhibitor;MDGI;M-FABP;muscle fatty acid-binding protein;O-FABP
Description (eCommerce)
The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They are thought to participate in the uptake, intracellular metabolism and transport of long-chain fatty acids and their acyl-CoA esters. FABP3 is the cardiac type of fatty acid binding protein FABP3 is a cytosolic protein found in cardiomyocytes. [taken from NCBI Entrez Gene (Gene ID: 2170)].
Description (Vector)
The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer.
Gene ID
2170
Gene Name (eCommerce)
fatty acid binding protein 3
Gene Name (Vector)
fatty acid binding protein 3
Gene Symbol
FABP3
HGNC ID
HGNC:3557
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
402
Protein Name (eCommerce)
Fatty acid-binding protein, heart
RefSeq ID
NM_004102
RefSeq Synonyms
NM_004102, NM_001320996, BC007021,
Research Areas (Faceted)
cell_biology,metabolism,signal_transduction
Species
human
Target Sentence
The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They are thought to participate in the uptake, intracellular metabolism and transport of long-chain fatty acids and their acyl-CoA esters. FABP3 is the cardiac type of fatty acid binding protein FABP3 is a cytosolic protein found in cardiomyocytes. [taken from NCBI Entrez Gene (Gene ID: 2170)].
UniGene ID
Hs.657242
UniProt ID (eCommerce)
P05413

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.