human EMD shRNA silencing AAV

Name 
AAV-h-EMD-shRNA
Cat No 
shAAV-207871
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human EMD.

shAAV-207871
AAV-h-EMD-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human EMD (emerin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
EDMD; emerin; LEM domain containing 5; LEMD5; STA
Description (eCommerce)
Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene [taken from NCBI Entrez Gene (Gene ID: 2010)].
Description (Vector)
Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene.
Gene ID
2010
Gene Name (eCommerce)
emerin
Gene Name (Vector)
emerin
Gene Symbol
EMD
HGNC ID
HGNC:3331
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
765
ORF Size (bp)
765 bp
Protein Name (eCommerce)
Emerin
RefSeq ID
NM_000117
RefSeq Synonyms
NM_000117, BC000738,
Research Areas
Cardiology,Cardiomyopathy,Cardiovascular,Cell Cycle,Cytoskeleton,Signal Transduction,Wnt Signaling
Research Areas (Faceted)
cardiovascular,cell_biology,cell_cycle,genetics,signal_transduction
Species
human
Target Sentence
Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene [taken from NCBI Entrez Gene (Gene ID: 2010)].
UniGene ID
Hs.522823
UniProt ID (eCommerce)
P50402

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.