human ELN shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ELN.
shAAV-207853
AAV-h-ELN-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ELN (elastin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
SVAS; WBS; WS
Description (Vector)
ELN encodes a protein that is one of the two components of elastic fibers. The encoded protein is rich in hydrophobic amino acids such as glycine and proline, which form mobile hydrophobic regions bounded by crosslinks between lysine residues. Deletions and mutations in this gene are associated with supravalvular aortic stenosis (SVAS) and autosomal dominant cutis laxa. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
2006
Gene Name (Vector)
elastin
Gene Symbol
ELN
HGNC ID
HGNC:3327
ORF Size (aa)
1977
ORF Size (bp)
1977 bp
RefSeq ID
NM_000501
RefSeq Synonyms
NM_001278939, NM_001278918, NM_001278917, NM_001278916, NM_001278915, NM_001278914, NM_001278913, NM_001278912, NM_001081755, NM_001081754, NM_001081753, NM_001081752, NM_000501, BC065566,
Species
human
UniGene ID
Hs.647061
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.