human EIF4EBP2 shRNA silencing AAV

Cat. No: shAAV-207789

Availability: 4-5 weeks

Name: AAV-h-EIF4EBP2-shRNA

This is an AAV expressing shRNA for silencing of Human EIF4EBP2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: EIF4EBP2
Gene Name: eukaryotic translation initiation factor 4E binding protein 2
Gene ID: 1979
Gene Synonyms: 4EBP2; PHASII
ORF Size: 363 bp
RefSeq#: NM_004096
Gene Description: EIF4EBP2 encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection.
UniGene ID: Hs.705686
HGNC ID: HGNC:3289