human EIF4EBP2 shRNA silencing AAV

Name 
AAV-h-EIF4EBP2-shRNA
Cat No 
shAAV-207789
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human EIF4EBP2.

shAAV-207789
AAV-h-EIF4EBP2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human EIF4EBP2 (eukaryotic translation initiation factor 4E binding protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
4EBP2; PHASII
Description (Vector)
EIF4EBP2 encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection.
Gene ID
1979
Gene Name (Vector)
eukaryotic translation initiation factor 4E binding protein 2
Gene Symbol
EIF4EBP2
HGNC ID
HGNC:3289
ORF Size (aa)
363
RefSeq ID
NM_004096
RefSeq Synonyms
NM_004096, BC050633, BC005057,
Species
human
UniGene ID
Hs.705686

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.