human EIF3B shRNA silencing AAV

Name 
AAV-h-EIF3B-shRNA
Cat No 
shAAV-207732
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human EIF3B.

shAAV-207732
AAV-h-EIF3B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human EIF3B (eukaryotic translation initiation factor 3 subunit B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
eIF3 p110; eIF3 p116; eIF3b; eIF-3-eta; EIF3-ETA; EIF3-P110; EIF3-P116; EIF3S9; eukaryotic translation initiation factor 3 subunit 9; eukaryotic translation initiation factor 3 subunit B; eukaryotic translation initiation factor 3, subunit 9 (eta, 116kD); eukaryotic translation initiation factor 3, subunit 9 eta, 116kDa; hPrt1; PRT1; prt1 homolog
Description (eCommerce)
Eukaryotic initiation factor 3 subunit B (eIF3B) is one of at least 13 non-identical protein subunits of eukaryotic initiation factor 3 (eIF3). eIF3 is the largest eIF (~650 kDa) and functions to facilitate binding of the 40S ribosomal subunit to the 5’-end of cellular mRNAs near the cap structure (m7GpppN). eIF3B is a conserved subunit and part of the functional core of eIF3. It bears a non-canonical RNA recognition motif (RRM) and interacts directly with the eIF3S1 subunit.
Gene ID
8662
Gene Name (eCommerce)
eukaryotic translation initiation factor 3 subunit B
Gene Name (Vector)
eukaryotic translation initiation factor 3 subunit B
Gene Symbol
EIF3B
HGNC ID
HGNC:3280
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2445
ORF Size (bp)
2445 bp
Protein Name (eCommerce)
Eukaryotic translation initiation factor 3 subunit B
RefSeq ID
NM_003751
RefSeq Synonyms
NM_003751, NM_001037283, BC110865, BC001173,
Research Areas
Gene Expression,Interleukin Signaling,Metabolism/Metabolic Process,mRNA Binding,RNA Binding,RNA Transport,Signal Transduction,Translational Control
Research Areas (Faceted)
signal_transduction,genetics,transcription_translation,signal_transduction,immunology,metabolism,genetics,cell_biology,genetics,transcription_translation
Species
human
Target Sentence
Eukaryotic initiation factor 3 subunit B (eIF3B) is one of at least 13 non-identical protein subunits of eukaryotic initiation factor 3 (eIF3). eIF3 is the largest eIF (~650 kDa) and functions to facilitate binding of the 40S ribosomal subunit to the 5’-end of cellular mRNAs near the cap structure (m7GpppN). eIF3B is a conserved subunit and part of the functional core of eIF3. It bears a non-canonical RNA recognition motif (RRM) and interacts directly with the eIF3S1 subunit.
UniGene ID
Hs.371001
UniProt ID (eCommerce)
P55884

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.