human ECM1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ECM1.
shAAV-207536
AAV-h-ECM1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ECM1 (extracellular matrix protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
URBWD
Description (Vector)
ECM1 encodes a soluble protein that is involved in endochondral bone formation, angiogenesis, and tumor biology. It also interacts with a variety of extracellular and structural proteins, contributing to the maintenance of skin integrity and homeostasis. Mutations in this gene are associated with lipoid proteinosis disorder (also known as hyalinosis cutis et mucosae or Urbach-Wiethe disease) that is characterized by generalized thickening of skin, mucosae and certain viscera. Alternatively spliced transcript variants encoding distinct isoforms have been described for this gene.
Gene ID
1893
Gene Name (Vector)
extracellular matrix protein 1
Gene Symbol
ECM1
HGNC ID
HGNC:3153
ORF Size (aa)
1623
ORF Size (bp)
1623 bp
RefSeq ID
NM_004425
RefSeq Synonyms
NM_022664, NM_004425, NM_001202858, BC023505,
Species
human
UniGene ID
Hs.81071
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.