human DDX39 shRNA silencing AAV

Name
AAV-h-DDX39-shRNA

Cat No
shAAV-206755

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human DDX39A.

shAAV-206755

AAV-h-DDX39-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DDX39A (DExD-box helicase 39A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

BAT1; BAT1L; DDX39; DDXL; URH49

Description (Vector)

DDX39A encodes a member of the DEAD box protein family. These proteins are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD) and are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Alternatively spliced transcript variants encoding different isoforms have been found.

Gene ID

10212

Gene Name (Vector)

DExD-box helicase 39A

Gene Symbol

DDX39A

HGNC ID

HGNC:17821

ORF Size (aa)

1284

ORF Size (bp)

1284 bp

RefSeq ID

NM_005804

RefSeq Synonyms

NM_005804, BC032128, BC010455, BC001009,

Species

human

UniGene ID

Hs.311609

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.