human DCTN5 shRNA silencing AAV

Name 
AAV-h-DCTN5-shRNA
Cat No 
shAAV-206680
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human DCTN5.

shAAV-206680
AAV-h-DCTN5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DCTN5 (dynactin subunit 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
DCTN5 encodes a subunit of dynactin, a component of the cytoplasmic dynein motor machinery involved in minus-end-directed transport. The encoded protein is a component of the pointed-end subcomplex and is thought to bind membranous cargo. A pseudogene of this gene is located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
84516
Gene Name (Vector)
dynactin subunit 5
Gene Symbol
DCTN5
HGNC ID
HGNC:24594
ORF Size (aa)
549
ORF Size (bp)
549 bp
RefSeq ID
NM_032486
RefSeq Synonyms
NM_032486, NM_001199743, NM_001199011, BC004191,
Species
human
UniGene ID
Hs.435941

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.