human DAD1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human DAD1.
shAAV-206571
AAV-h-DAD1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human DAD1 (defender against cell death 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
OST2
Description (Vector)
DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes.
Gene ID
1603
Gene Name (Vector)
defender against cell death 1
Gene Symbol
DAD1
HGNC ID
HGNC:2664
ORF Size (aa)
342
RefSeq ID
NM_001344
RefSeq Synonyms
NM_001344, BC009798, BC007403,
Species
human
UniGene ID
Hs.82890
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.