human DAD1 shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-206571
Availability:
3-5 weeks
Name:
Ad-h-DAD1-shRNA
This is an Adenovirus expressing shRNA for silencing of Human DAD1.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- DAD1
- Gene Name
- defender against cell death 1
- Gene ID
- 1603
- Gene Synonyms
- OST2
- ORF Size
- 342 bp
- RefSeq#
- NM_001344
- Gene Description
- DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes.
- UniGene ID
- Hs.82890
- HGNC ID
- HGNC:2664
Related Products
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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