human CYTSB shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SPECC1.
shAAV-206553
AAV-h-CYTSB-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SPECC1 (sperm antigen with calponin homology and coiled-coil domains 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
cytokinesis and spindle organization B; cytospin-B; CYTSB; HCMOGT1; HCMOGT-1; NSP; NSP5; nuclear structure protein 5; sperm antigen HCMOGT-1; Sperm antigen with calponin homology and coiled-coil domains 1; sperm antigen with calponin-like and coiled coil domains 1; structure protein NSP5a3a; structure protein NSP5a3b; structure protein NSP5b3a; structure protein NSP5b3b
Description (eCommerce)
SPECC1 (sperm antigen with calponin homology and coiled-coil domains 1) was cloned as part of as part of a chromosomal translocation involving PDGFRB in a case of juvenile myelomonocytic leukemia.
Description (Vector)
SPECC1 belongs to the cytospin-A family. It is localized in the nucleus, and highly expressed in testis and some cancer cell lines. A chromosomal translocation involving this gene and platelet-derived growth factor receptor, beta gene (PDGFRB) may be a cause of juvenile myelomonocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Gene ID
92521
Gene Name (eCommerce)
sperm antigen with calponin homology and coiled-coil domains 1
Gene Name (Vector)
sperm antigen with calponin homology and coiled-coil domains 1
Gene Symbol
SPECC1
HGNC ID
HGNC:30615
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2964
ORF Size (bp)
2964 bp
Protein Name (eCommerce)
Cytospin-B
RefSeq ID
NM_152904
RefSeq Synonyms
NM_152904, NM_001243439, NM_001243438, NM_001033555, NM_001033554, NM_001033553, BC050058, BC021123,
Research Areas
Cancer
Research Areas (Faceted)
cancer
Species
human
Target Sentence
SPECC1 (sperm antigen with calponin homology and coiled-coil domains 1) was cloned as part of as part of a chromosomal translocation involving PDGFRB in a case of juvenile myelomonocytic leukemia.
UniGene ID
Hs.431045
UniProt ID (eCommerce)
Q5M775
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.