human CRNN shRNA silencing AAV

Name
AAV-h-CRNN-shRNA

Cat No
shAAV-206031

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human CRNN.

shAAV-206031

AAV-h-CRNN-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CRNN (cornulin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

C1orf10; DRC1; PDRC1; SEP53

Description (Vector)

CRNN encodes a member of the 'fused gene' family of proteins, which contain N-terminus EF-hand domains and multiple tandem peptide repeats. The encoded protein contains two EF-hand Ca2+ binding domains in its N-terminus and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. This gene, also known as squamous epithelial heat shock protein 53, may play a role in the mucosal/epithelial immune response and epidermal differentiation.

Gene ID

49860

Gene Name (Vector)

cornulin

Gene Symbol

CRNN

HGNC ID

HGNC:1230

ORF Size (aa)

1488

ORF Size (bp)

1488 bp

RefSeq ID

NM_016190

RefSeq Synonyms

NM_016190, BC030807,

Species

human

UniGene ID

Hs.242057

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.