human CRLF1 shRNA silencing AAV

Name
AAV-h-CRLF1-shRNA

Cat No
shAAV-206024

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human CRLF1.

shAAV-206024

AAV-h-CRLF1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CRLF1 (cytokine receptor like factor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CISS; CISS1; CLF; CLF-1; NR6; zcytor5

Description (Vector)

CRLF1 encodes a member of the cytokine type I receptor family. The protein forms a secreted complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors. The complex can promote survival of neuronal cells. Mutations in this gene result in Crisponi syndrome and cold-induced sweating syndrome.

Gene ID

9244

Gene Name (Vector)

cytokine receptor like factor 1

Gene Symbol

CRLF1

HGNC ID

HGNC:2364

ORF Size (aa)

1269

ORF Size (bp)

1269 bp

RefSeq ID

NM_004750

RefSeq Synonyms

NM_004750, BC044634,

Species

human

UniGene ID

Hs.114948

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.