human CPT1B shRNA silencing AAV

Name
AAV-h-CPT1B-shRNA

Cat No
shAAV-205941

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human CPT1B.

shAAV-205941

AAV-h-CPT1B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CPT1B (carnitine palmitoyltransferase 1B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CPT1-M; CPT1M; CPTI; CPTI-M; M-CPT1; MCCPT1; MCPT1

Description (Vector)

CPT1B, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene.

Gene ID

1375

Gene Name (Vector)

carnitine palmitoyltransferase 1B

Gene Symbol

CPT1B

HGNC ID

HGNC:2329

ORF Size (aa)

2319

ORF Size (bp)

2319 bp

RefSeq ID

NM_004377

RefSeq Synonyms

NM_152246, NM_152245, NM_004377, NM_001145137, NM_001145136, NM_001145135, NM_001145134, BC150318, BC143071, BC142954, BC131570,

Species

human

UniGene ID

Hs.439777

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.