human CPN1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CPN1.
shAAV-205899
AAV-h-CPN1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CPN1 (carboxypeptidase N subunit 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CPN; SCPN
Description (Vector)
Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency.
Gene ID
1369
Gene Name (Vector)
carboxypeptidase N subunit 1
Gene Symbol
CPN1
HGNC ID
HGNC:2312
ORF Size (aa)
1377
ORF Size (bp)
1377 bp
RefSeq ID
NM_001308
RefSeq Synonyms
NM_001308, BC027897,
Species
human
UniGene ID
Hs.2246
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.