human COX8A shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human COX8A.
shAAV-205862
AAV-h-COX8A-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human COX8A (cytochrome c oxidase subunit 8A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
COX; COX8; COX8-2; COX8L; VIII; VIII-L
Description (Vector)
COX8A is the terminal enzyme of the respiratory chain, coupling the transfer of electrons from cytochrome c to molecular oxygen, with the concomitant production of a proton electrochemical gradient across the inner mitochondrial membrane. In addition to 3 mitochondrially encoded subunits, which perform the catalytic function, the eukaryotic enzyme contains nuclear-encoded smaller subunits, ranging in number from 4 in some organisms to 10 in mammals. It has been proposed that nuclear-encoded subunits may be involved in the modulation of the catalytic function. This gene encodes one of the nuclear-encoded subunits.
Gene ID
1351
Gene Name (Vector)
cytochrome c oxidase subunit 8A
Gene Symbol
COX8A
HGNC ID
HGNC:2294
ORF Size (aa)
210
RefSeq ID
NM_004074
RefSeq Synonyms
NM_004074, BC063025,
Species
human
UniGene ID
Hs.433901
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.