human COLQ shRNA silencing AAV

Name
AAV-h-COLQ-shRNA

Cat No
shAAV-205729

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human COLQ.

shAAV-205729

AAV-h-COLQ-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human COLQ (collagen like tail subunit of asymmetric acetylcholinesterase). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CMS5; EAD

Description (Vector)

COLQ encodes the subunit of a collagen-like molecule associated with acetylcholinesterase in skeletal muscle. Each molecule is composed of three identical subunits. Each subunit contains a proline-rich attachment domain (PRAD) that binds an acetylcholinesterase tetramer to anchor the catalytic subunit of the enzyme to the basal lamina. Mutations in this gene are associated with endplate acetylcholinesterase deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID

8292

Gene Name (Vector)

collagen like tail subunit of asymmetric acetylcholinesterase

Gene Symbol

COLQ

HGNC ID

HGNC:2226

ORF Size (aa)

1368

ORF Size (bp)

1368 bp

RefSeq ID

NM_005677

RefSeq Synonyms

NM_080539, NM_080538, NM_005677, BC074829, BC074828,

Species

human

UniGene ID

Hs.146735

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.