human COL9A3 shRNA silencing AAV

Name
AAV-h-COL9A3-shRNA

Cat No
shAAV-205723

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human COL9A3.

shAAV-205723

AAV-h-COL9A3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human COL9A3 (collagen type IX alpha 3 chain). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

DJ885L7.4.1; EDM3; IDD; MED

Description (Vector)

COL9A3 encodes one of the three alpha chains of type IX collagen, the major collagen component of hyaline cartilage. Type IX collagen, a heterotrimeric molecule, is usually found in tissues containing type II collagen, a fibrillar collagen. Mutations in this gene are associated with multiple epiphyseal dysplasia type 3.

Gene ID

1299

Gene Name (Vector)

collagen type IX alpha 3 chain

Gene Symbol

COL9A3

HGNC ID

HGNC:2219

ORF Size (aa)

2055

ORF Size (bp)

2055 bp

RefSeq ID

NM_001853

RefSeq Synonyms

NM_001853, BC011705,

Species

human

UniGene ID

Hs.716639

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.