human COL4A6 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human COL4A6.
shAAV-205710
AAV-h-COL4A6-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human COL4A6 (collagen type IV alpha 6 chain). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CXDELq22.3; DELXq22.3; DFNX6
Description (Vector)
COL4A6 encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Two splice variants have been identified for this gene.
Gene ID
1288
Gene Name (Vector)
collagen type IV alpha 6 chain
Gene Symbol
COL4A6
HGNC ID
HGNC:2208
ORF Size (aa)
4902
ORF Size (bp)
4902 bp
RefSeq ID
NM_001847
RefSeq Synonyms
NM_033641, NM_001847, NM_001287760, NM_001287759, NM_001287758, BC144669, BC140855, BC005305,
Species
human
UniGene ID
Hs.145586
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.