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human COL12A1 shRNA silencing AAV

Name 
AAV-h-COL12A1-shRNA
Cat No 
shAAV-205680
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human COL12A1.

shAAV-205680
AAV-h-COL12A1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human COL12A1 (collagen type XII alpha 1 chain). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BA209D8.1; BTHLM2; COL12A1L; DJ234P15.1; UCMD2
Description (Vector)
COL12A1 encodes the alpha chain of type XII collagen, a member of the FACIT (fibril-associated collagens with interrupted triple helices) collagen family. Type XII collagen is a homotrimer found in association with type I collagen, an association that is thought to modify the interactions between collagen I fibrils and the surrounding matrix. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID
1303
Gene Name (Vector)
collagen type XII alpha 1 chain
Gene Symbol
COL12A1
HGNC ID
HGNC:2188
ORF Size (aa)
5700
ORF Size (bp)
5700 bp
RefSeq ID
NM_004370
RefSeq Synonyms
NM_080645, NM_004370, BC146868,
Species
human
UniGene ID
Hs.101302

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.