human CNGB3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CNGB3.
shAAV-205578
AAV-h-CNGB3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CNGB3 (cyclic nucleotide gated channel beta 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ACHM1
Description (Vector)
CNGB3 encodes the beta subunit of a cyclic nucleotide-gated ion channel. The encoded beta subunit appears to play a role in modulation of channel function in cone photoreceptors. This heterotetrameric channel is necessary for sensory transduction, and mutations in this gene have been associated with achromatopsia 3, progressive cone dystrophy, and juvenile macular degeneration, also known as Stargardt Disease.
Gene ID
54714
Gene Name (Vector)
cyclic nucleotide gated channel beta 3
Gene Symbol
CNGB3
HGNC ID
HGNC:2153
ORF Size (aa)
2430
ORF Size (bp)
2430 bp
RefSeq ID
NM_019098
RefSeq Synonyms
NM_019098, BC150601,
Species
human
UniGene ID
Hs.154433
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.