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human CNGB3 Over-expression AAV

Name 
AAV-h-CNGB3
Cat No 
AAV-205578
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CNGB3.

AAV-205578
AAV-h-CNGB3

Ready-to-use AAV expressing Human CNGB3 (cyclic nucleotide gated channel beta 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ACHM1
Description (Vector)
CNGB3 encodes the beta subunit of a cyclic nucleotide-gated ion channel. The encoded beta subunit appears to play a role in modulation of channel function in cone photoreceptors. This heterotetrameric channel is necessary for sensory transduction, and mutations in this gene have been associated with achromatopsia 3, progressive cone dystrophy, and juvenile macular degeneration, also known as Stargardt Disease.
Gene ID
54714
Gene Name (Vector)
cyclic nucleotide gated channel beta 3
Gene Symbol
CNGB3
HGNC ID
HGNC:2153
ORF Size (aa)
2430
ORF Size (bp)
2430 bp
RefSeq ID
NM_019098
RefSeq Synonyms
NM_019098, BC150601,
Species
human
UniGene ID
Hs.154433

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.