human CLTA shRNA silencing AAV

Name
AAV-h-CLTA-shRNA

Cat No
shAAV-205522

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human CLTA.

shAAV-205522

AAV-h-CLTA-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CLTA (clathrin light chain A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

LCA

Description (Vector)

Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 8 and 12.

Gene ID

1211

Gene Name (Vector)

clathrin light chain A

Gene Symbol

CLTA

HGNC ID

HGNC:2090

ORF Size (aa)

657

ORF Size (bp)

657 bp

RefSeq ID

NM_001833

RefSeq Synonyms

NM_007096, NM_001833, NM_001311206, NM_001311205, NM_001311204, NM_001311203, NM_001184762, NM_001184761, NM_001184760, NM_001076677, BC019287, BC009201,

Species

human

UniGene ID

Hs.522114

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.