human CLEC12A shRNA silencing AAV

Name
AAV-h-CLEC12A-shRNA

Cat No
shAAV-205401

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human CLEC12A.

shAAV-205401

AAV-h-CLEC12A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CLEC12A (C-type lectin domain family 12 member A). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CD371; CLL-1; CLL1; DCAL-2; MICL

Description (Vector)

CLEC12A encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. CLEC12A is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13.

Gene ID

160364

Gene Name (Vector)

C-type lectin domain family 12 member A

Gene Symbol

CLEC12A

HGNC ID

HGNC:31713

ORF Size (aa)

642

ORF Size (bp)

642 bp

RefSeq ID

NM_138337

RefSeq Synonyms

NM_201623, NM_138337, NM_001300730, NM_001207010, BC126291, BC126289, BC063424,

Species

human

UniGene ID

Hs.190519

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.