human CLCA1 shRNA silencing AAV

Name
AAV-h-CLCA1-shRNA

Cat No
shAAV-205338

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human CLCA1.

shAAV-205338

AAV-h-CLCA1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CLCA1 (chloride channel accessory 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CACC; CaCC-1; CACC1; CLCRG1; GOB5; hCaCC-1; hCLCA1

Description (Vector)

CLCA1 encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions. The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although the site at which the precursor is cleaved has not been precisely determined. The encoded protein may be involved in mediating calcium-activated chloride conductance in the intestine.

Gene ID

1179

Gene Name (Vector)

chloride channel accessory 1

Gene Symbol

CLCA1

HGNC ID

HGNC:2015

ORF Size (aa)

2742

ORF Size (bp)

2742 bp

RefSeq ID

NM_001285

RefSeq Synonyms

NM_001285, BC156805, BC141451,

Species

human

UniGene ID

Hs.194659

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.