human CKAP4 shRNA silencing AAV

Name 
AAV-h-CKAP4-shRNA
Cat No 
shAAV-205309
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CKAP4.

shAAV-205309
AAV-h-CKAP4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CKAP4 (cytoskeleton associated protein 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
63 kDa membrane protein; 63-kDa cytoskeleton-linking membrane protein; CLIMP-63; cytoskeleton-associated protein 4; ERGIC-63; p63; transmembrane protein (63kD), endoplasmic reticulum/Golgi intermediate compartment; type-II transmembrane protein p63
Description (eCommerce)
Cytoskeleton-associated protein 4 (CKAP4) is also known as p63 and cytoskeleton-linking membrane protein 63kDa (CLIMP-63). It was first described as a palmitoylated single-pass transmembrane receptor that localized to the rough endoplasmic reticulum as well as the cell membrane. CKAP4 has been shown to help anchor endoplasmic reticulum to microtubules.
Gene ID
10970
Gene Name (eCommerce)
cytoskeleton associated protein 4
Gene Name (Vector)
cytoskeleton associated protein 4
Gene Symbol
CKAP4
HGNC ID
HGNC:16991
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1569
ORF Size (bp)
1569 bp
Protein Name (eCommerce)
Cytoskeleton-associated protein 4
RefSeq ID
NM_006825
RefSeq Synonyms
NM_006825, BC094824, BC082972,
Research Areas
Cytoskeleton
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Cytoskeleton-associated protein 4 (CKAP4) is also known as p63 and cytoskeleton-linking membrane protein 63kDa (CLIMP-63). It was first described as a palmitoylated single-pass transmembrane receptor that localized to the rough endoplasmic reticulum as well as the cell membrane. CKAP4 has been shown to help anchor endoplasmic reticulum to microtubules.
UniGene ID
Hs.714862
UniProt ID (eCommerce)
Q07065

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.