human CISD2 shRNA silencing AAV

Name 
AAV-h-CISD2-shRNA
Cat No 
shAAV-205294
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CISD2.

shAAV-205294
AAV-h-CISD2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CISD2 (CDGSH iron sulfur domain 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ERIS; Miner1; NAF-1; WFS2; ZCD2
Description (Vector)
CISD2 is a zinc finger protein that localizes to the endoplasmic reticulum. The encoded protein binds an iron/sulfur cluster and may be involved in calcium homeostasis. Defects in this gene are a cause of Wolfram syndrome 2.
Gene ID
493856
Gene Name (Vector)
CDGSH iron sulfur domain 2
Gene Symbol
CISD2
HGNC ID
HGNC:24212
ORF Size (aa)
408
ORF Size (bp)
408 bp
RefSeq ID
NM_001008388
RefSeq Synonyms
NM_001008388, BC032300,
Species
human
UniGene ID
Hs.707333

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.